Table 2 Characteristics of the participants stratified according to the ALDH2 genetic polymorphism
*1/*1 | *1/*2 or *2/*2 | P value | |
|---|---|---|---|
(n = 767) | (n = 458) | ||
Age (years) | 42.5 ± 8.7 | 42.7 ± 8.4 | 0.681 |
Height (cm) | 169.4 ± 5.9 | 169.1 ± 6.2 | 0.344 |
Weight (kg) | 67.6 ± 9.8 | 66.6 ± 9.5 | 0.700 |
BMI (kg/m2) | 23.5 ± 3.0 | 23.3 ± 2.9 | 0.116 |
SBP (mmHg) | 125.5 ± 13.7 | 122.2 ± 13.6 | <0.001 |
DBP (mmHg) | 78.6 ± 10.5 | 76.0 ± 11.0 | <0.001 |
ASTa | 25.9 ± 13.7 | 22.5 ± 8.6 | <0.001 |
ALTa | 33.9 ± 22.5 | 27.1 ± 15.9 | <0.001 |
γ-GTPa | 75.2 ± 81.0 | 46.1 ± 37.8 | <0.001 |
TCa | 201.8 ± 35.5 | 195.5 ± 34.4 | 0.002 |
LDLa | 114.2 ± 34.7 | 115.1 ± 31.3 | 0.632 |
HDLa | 61.0 ± 14.7 | 56.9 ± 14.0 | <0.001 |
TGa | 153.4 ± 152.5 | 138.8 ± 125.4 | 0.046 |
Amount of daily alcohol intake (g) | 19.6 ± 25.5 | 15.6 ± 22.4 | 0.004 |
Classification of daily alcohol intake (%) | 0.019 | ||
None | 324 (42.2) | 228 (49.8) | |
6–15 g/day | 139 (18.1) | 87 (19.0) | |
16–32 g/day | 147 (19.2) | 75 (16.4) | |
More than 33 g/day | 157 (20.5) | 68 (14.8) | |
Smoking status (%) | 0.589 | ||
None | 322 (42.0) | 195 (42.6) | |
1–20 cigarettes/day | 364 (47.5) | 207 (45.2) | |
More than 21 cigarettes/day | 81 (10.6) | 56 (12.2) | |
Presence of HT (%) | 0.055 | ||
Control group | 630 (82.1) | 396 (86.5) | |
HT group | 137 (17.9) | 62 (13.5) | |