Mesothelin (MSLN) methylation and soluble mesothelin-related protein levels in a Chinese asbestos-exposed population

Table 3 Influences of covariates, asbestos exposure, non-alignment ARDs on SMRP in multiple linear regression

	Parameter	Coefficient	SE	95 % CI	P value
Log (SMRP)	Age	0.014	0.10	−0.005 to 0.034	0.154
	Gender	0.090	0.125	−0.155 to 0.336	0.470
	Creatinine	0.005	0.004	−0.003 to 0.013	0.235
	egfr	−0.002	0.009	−0.020 to 0.016	0.826
	BMI	−0.059	0.012	−0.083 to −0.034	<0.0001
	Smoking	0.356	0.394	0.421 to 1.134	0.367
	Cigarette/day	−0.21	0.28	−0.077 to 0.035	0.465
	Group 2	−0.042	0.177	−0.391 to 0.307	0.812*
	Group 3	0.430	0.159	0116 to 0.743	0.007*
	Group 4	0.242	0.167	−0.089 to 0.572	0.151*
	Group 5	0.708	0.193	0.328 to 1.088	<0.0001*
	Group 6	0.698	0.226	0.253 to 1.143	0.002 *
	Group 7	0.249	0.159	−0.059 to 0.558	0.112*

Group 2: healthy subjects only non-occupationally exposed to asbestos; group 3: healthy subjects only occupationally exposed to asbestos (asbestos textile); group 4: healthy subjects both non-occupationally and occupationally exposed to asbestos (mixed exposure); group 5: subjects with asbestosis and pleural plaque; group 6: subjects with asbestosis; group 7: subjects with pleural plaque
* Compared with group 1: healthy participants without asbestos exposure

ISSN: 1347-4715