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Table 1 General characteristics of the study participants

From: Mesothelin (MSLN) methylation and soluble mesothelin-related protein levels in a Chinese asbestos-exposed population

 

Group 1 (n = 45)

Group 2 (n = 27)

Group 3 (n = 56)

Group 4 (n = 40)

Group 5 (n = 26)

Group 6 (n = 17)

Group 7 (n = 51)

Age year (mean ± SD)

56.7 ± 10.2

69.4 ± 7.7

65.3 ± 7.1

65.8 ± 6.3

63.8 ± 5.9

71.1 ± 5.9

64.2 ± 4.5

Gender (n) male/female|

21/24

27/0

9/47

8/32

6/20

5/12

14/37

Body mass index, % (n)

 <18.5

2.2 (1)

3.7 (1)

7.1 (4)

5 (2)

0

11.8 (2)

11.8 (6)

 18.5–24.9

44.4 (20)

81.5 (22)

62.5 (35)

47.5 (19)

57.7 (15)

35.3 (6)

62.7 (32)

 25–29.9

6.7 (4)

14.8 (4)

16.1 (9)

22.5 (9)

11.5 (3)

17.6 (3)

21.6 (11)

 ≥30

0 (0)

0

3.6 (2)

7.5 (3)

0

5.9 (1)

0

 Unavailable

46.7 (20)

0

10.7 (6)

17.5 (7)

30.8 (8)

29.4 (5)

3.9 (2)

Smoker (%)

17.8

33.3

3.6

12.5

7.7

5.9

11.8

Exposure time year (mean ± SD)

–

NA

8.6 ± 5.0

8.6 ± 7.3

10.8 ± 6.1

8.0 ± 5.3

9.5 ± 5.4

Potential exposure level mg/m3 × year (median with IQ25–75)

–

NA

7 (3.7–14.4)

20.7 (7–50.2)

11.2 (3.9–100.3)

29.5 (9.4–50.2)

29.5 (3.9–59)

Creatine in μmol/L (median and range)

57 (42–89)

77 (58–101)

60 (42–205)

60 (34–93)

58.5 (40–103)

67 (43–92)

61 (44–152)

Blood urea nitrogen in mmol/L (median and range)

5.2 (2.6–7.8)

5.3 (4.2–11.4)

5.4 (2.6–14.5)

6.0 (3.6–7.6)

5.4 (3.2–9.1)

6.1 (3.8–9.6)

5.7 (2.3–10.6)

eGFR in mL/min/1.73 m2 (mean + SD)

91.6 ± 12.0

75.5 ± 7.7

84.7 ± 11.5

84.5 ± 10.0

86.8 ± 8.9

78.6 ± 9.3

85.4 ± 7.9

  1. Group 1 healthy controls without asbestos exposure; group 2 healthy subject only non-occupationally exposed to asbestos; group 3 healthy subjects only occupationally exposed to asbestos (asbestos textile); group 4 healthy subjects both non-occupationally and occupationally exposed to asbestos (mixed exposure); group 5 asbestosis and pleural plaque; group 6 asbestosis; group 7 pleural plaque