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Table 3 Relationships between the expression levels of selected biomarkers and the distance from the child’s home to the nearest large road among all study subjects as well as among two sub-groups based on the subjects’ food-specific IgE status [19]

From: Useful biomarkers for assessing the adverse health effects of PCBs in allergic children: pediatric molecular epidemiology

Primer

All

Negative (egg and milk and wheat)

Positive (egg and/or milk and/or wheat)

≥50 m (N = 22)

<50 m (N = 8)

P value

≥50 m (N = 6)

<50 m (N = 2)

P value

≥50 m (N = 16)

<50 m (N = 6)

P value

Median (95 % CI)

Median (95 % CI)

Median (95 % CI)

Median (95 % CI)

Median (95 % CI)

Median (95 % CI)

IL-6

1.25 (0.99, 2.69)

1.85 (1.14, 5.24)

0.348

0.89 (0.45, 12.9)

1.57 (0.90, 2.25)

0.739

1.28 (1.07, 2.73)

1.85 (1.27, 6.46)

0.238

IL-8

1.02 (0.75, 1.81)

1.65 (0.81, 3.95)

0.174

1.45 (1.00, 2.34)

1.17 (0.63, 1.71)

0.505

0.96 (0.59, 2.06)

2.03 (0.96, 6.46)

0.090

IL-10

2.52 (1.63, 3.33)

2.00 (0.95, 2.54)

0.205

2.88 (1.05, 7.77)

1.74 (1.32, 2.17)

0.317

2.43 (1.57, 3.53)

2.00 (0.35, 2.68)

0.461

IL-17

1.47 (1.23, 1.56)

1.69 (1.09, 2.34)

0.425

0.73 (0.30, 1.71)

1.19 (1.18, 1.20)

0.505

1.51 (1.28, 2.13)

1.86 (0.98, 2.46)

0.302

IL-22

28.3 (9.51, 56.9)

119 (42.8, 318)

0.010

2.39 (0.95, 33.1)

54.6 (53.0, 56.2)

0.046

47.8 (21.1, 90.8)

231 (27.9, 325)

0.023

COX2

0.59 (0.42, 1.01)

0.79 (0.29, 1.00)

0.888

0.97 (0.21, 1.16)

0.50 (0.11, 0.89)

0.182

0.49 (0.39, 0.95)

0.79 (0.41, 1.11)

0.269

CYP1A1

6.86 (1.75, 8.28)

14.2 (7.33, 32.5)

0.010

1.25 (0.65, 6.83)

11.6 (9.92, 13.2)

0.046

7.32 (3.57, 12.4)

16.0 (5.74, 40.4)

0.065

Foxp3

1.55 (1.24, 1.86)

1.72 (1.07, 2.03)

0.673

0.72 (0.38, 1.88)

1.12 (1.10, 1.14)

0.505

1.61 (1.29, 2.24)

1.82 (1.07, 2.22)

0.507

SOCS3

1.57 (1.27, 1.78)

1.81 (1.11, 2.08)

0.425

0.71 (0.36, 1.85)

1.18 (1.15, 1.20)

0.505

1.65 (1.31, 2.21)

1.91 (1.10, 2.30)

0.338

RelB

1.61 (1.29, 1.86)

1.85 (1.10, 2.13)

0.512

0.71 (0.36, 1.95)

1.14 (1.14, 1.15)

0.505

1.67 (1.34, 2.28)

1.92 (1.11, 2.35)

0.376

  1. Bold values indicate siginificant results
  2. P values were obtained using the Mann–Whitney U test; N = 30