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Table 2 Concentration-dependent associations between the concentrations of individual and total PCB and the mRNA expression level of IL-8 among all subjects, the non-asthmatic (control) subjects and the asthmatic subjects [18]

From: Useful biomarkers for assessing the adverse health effects of PCBs in allergic children: pediatric molecular epidemiology

 

IL-8

Coefficient

SE

P for trend*

PCB #163 + #164

 All

0.164

0.070

0.021

 Control

0.064

0.097

0.480

 Asthma

0.270

0.115

0.022

PCB #170

 All

0.153

0.071

0.032

 Control

0.068

0.099

0.465

 Asthma

0.217

0.109

0.046

PCB #177

 All

0.164

0.070

0.021

 Control

0.064

0.097

0.480

 Asthma

0.270

0.115

0.022

PCB #178

 All

0.164

0.070

0.021

 Control

0.064

0.097

0.480

 Asthma

0.270

0.115

0.022

PCB #180 + #193

 All

0.154

0.071

0.032

 Control

0.068

0.099

0.465

 Asthma

0.217

0.109

0.046

Total PCBs

 All

0.133

0.073

0.065

 Control

0.064

0.097

0.480

 Asthma

0.180

0.128

0.145

  1. In each correlation study, PCB levels were first stratified by tertile and then assessed using univariate regression analysis
  2. Coefficient: regression coefficient
  3. SE standard error
  4. * P for trend was obtained using a univariate regression model