Table 4 Associations between the TAP1 genotype and CRC when stratified by gender
Gender | Genotype | Controls | Cases | Crude OR (95 % CI) | Adjusted OR (95 % CI) |
|---|---|---|---|---|---|
Male | C/C (%) | 55 (41.4) | 25 (27.8) | – | – |
C/T (%) | 67 (50.4) | 55 (61.1) | 1.81 (1.00–3.25)* | 2.04 (1.11–3.84)* | |
T/T (%) | 11 (8.27) | 10 (11.1) | 2.00 (0.77–5.22) | 2.38 (0.86–6.61) | |
Total | 133 | 90 | |||
C/T + T/T (%) | 78 (58.6) | 65 (72.2) | 1.83 (1.03–3.25)* | 2.09 (1.15–3.87)* | |
Female | C/C (%) | 51 (46.4) | 13 (24.5) | – | – |
C/T (%) | 48 (43.6) | 36 (67.9) | 2.94 (1.41–6.15)** | 2.91 (1.40–6.32)** | |
T/T (%) | 11 (10.0) | 4 (7.55) | 1.42 (0.41–4.95) | 1.45 (0.36–5.10) | |
Total | 110 | 53 | |||
C/T + T/T (%) | 59 (53.6) | 40 (75.5) | 2.66 (1.29–5.46)** | 2.63 (1.29–5.62)** |