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Table 2 Associations between the TAP1 genotype and CRC

From: The genotype of the transporter associated with antigen processing gene affects susceptibility to colorectal cancer in Japanese

Genotype

Controls

Cases

Crude OR (95 % CI)

Adjusted OR (95 % CI)

C/C (%)

106 (43.6)

38 (26.6)

C/T (%)

115 (47.3)

91 (63.6)

2.21 (1.39–3.49)**

2.27 (1.43–3.67)**

T/T (%)

22 (9.05)

14 (9.79)

1.78 (0.83–3.78)

1.95 (0.88–4.30)

Total

243

143

  

C/T + T/T (%)

137 (56.4)

105 (73.4)

2.14 (1.37–3.34)**

2.22 (1.42–3.55)**

  1. Crude OR and adjusted OR for age, gender and smoking status were estimated using Chi square statistic and multivariate logistic regression, respectively
  2. 95 % CI 95 % confidence interval, OR odds ratio
  3. * P < 0.05, ** P < 0.01