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Table 3 Species difference in the maximum velocity value and Michaelis constant of lipase activity for di(2-ethylhexyl)phthalate in hepatic microsomes from human and mouse

From: Species and inter-individual differences in metabolic capacity of di(2-ethylhexyl)phthalate (DEHP) between human and mouse livers

Reaction parameters

Human

Mouse

K m (mmol/L)

0.0144

0.0076

V max (nmol/mg protein/min)

1.52

5.45

V max/K m ratio

106

714

  1. K m Michaelis constant, V max maximum velocity value of the reaction
  2. Values are presented as the means of the results using three pooled samples per each concentration