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Table 4 Urinary phytoestrogen concentrations in equol producers and non-producers

From: Levels of urinary isoflavones and lignan polyphenols in Japanese women

Equol producers and non-producers

Isoflavones (soybean)a

Lignan polyphenols (sesame seeds)a

Equol (μg/g-Cr)

Daidzein (μg/g-Cr)

Enterolactone (μg/g-Cr)

Enterodiol (μg/g-Cr)

Total

 E(+)

564 (4.0)

1,531 (4.6)

56.7 (4.4)***

62.4 (4.4)***

 (n  = 195)

565

1,825

63.1

74.8

 E(−)

1,662 (4.5)

27.8 (6.9)

12.8 (7.3)

 (n = 305)

2,010

30.6

10.1

Hokkaido

 E(+)

681 (3.7)

1,738 (4.8)

57.3 (4.4)

48.3 (3.7)***

 (n = 30)

916

1,779

42.7

58.6

 E(−)

1,420 (5.4)

27.9 (6.8)

13.0 (7.9)

 (n = 70)

1,758

46.3

11.54

Miyagi

 E(+)

606 (3.9)

1,191 (4.8)

35.7 (4.8)

54.4 (4.1)***

 (n = 47)

636

1,324

41.8

70.8

 E(−)

1,736 (4.5)

23.7 (7.2)

8.6 (7.1)

 (n = 53)

2,292

27.7

5.8

Kyoto

 E(+)

614 (4.3)

1,164 (4.1)

70.9 (4.0)

101.7 (3.4)***

 (n = 38)

518

1,265

68.1

88.8

 E(−)

1,448 (5.0)

38.7 (7.5)

19.9 (8.1)

 (n = 62)

1,976

38.7

17.7

Kochi

 E(+)

404 (4.7)

1,361 (6.0)

78.1 (3.7)**

62.5 (4.8)***

 (n = 40)

382

1,647

78.6

61.1

 E(−)

1,459 (5.4)

27.4 (6.9)

13.7 (7.3)

 (n = 60)

1,536

22.4

9.2

Okinawa

 E(+)

579 (3.5)

2,745 (3.1)

56.6 (4.6)**

54.4 (5.6)***

 (n = 40)

490

3,520

70.3

64.6

 E(−)

2,533 (2.3)

22.5 (6.1)

10.4 (5.9)

 (n = 60)

2,570

24.5

6.0

  1. ** p < 0.01, *** p < 0.001, vs. equol non-producers by Student’s t test after log-transformation
  2. E(+) Equol producers, E(−) equol non-producers, Cr creatinine
  3. aUrinary phytoestrogen concentrations for equol producers and non-producers in the total study cohort and for each study region are given as: GM (GSD) (top row) and median (bottom row)