Environmental Health and Preventive Medicine

Table 2 The induction of folate deficiency and anemic phenotype

From: Folate-deficiency induced cell-specific changes in the distribution of lymphocytes and granulocytes in rats

Parameters	Group		FAD/CON^a
Parameters	CON	FAD	FAD/CON^a
Body weight (g)	508 ± 8	494 ± 6	0.97
Body weight gain (g)	323 ± 5	307 ± 6	0.95
Total food intake (kg)	1.22 ± 0.01	1.21 ± 0.01	0.99
Food efficiency^a	0.26 ± 0.004	0.25 ± 0.005	0.96
Total water intake (kg)	1.75 ± 0.08	1.73 ± 0.06	1.00
Plasma folic acid (ng/ml)	44.0 ± 2.5	1.6 ± 0.1***	0.04
Plasma homocysteine (nmol/ml)	4.7 ± 2.0	24.3 ± 2.1***	5.13
Red blood cells (×10⁴/μl)	920 ± 7.8	862 ± 12.1***	0.94
Hemoglobin (g/dl)	17.0 ± 0.2	16.3 ± 0.2**	0.96
Hematocrit (%)	46.2 ± 0.4	43.7 ± 0.5***	0.94

**p < 0.01 and ***p < 0.001 (vs. CON groups)
Data are presented as the mean ± standard error of the mean (SEM) (n = 10–12)
^aData are given as the relative ratios of the FAD groups to the CON groups

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