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Table 4 Sex-stratified, age-adjusted univariate and multivariate Cox proportional models for CKDu disease progression and death

From: Risk factors associated with disease progression and mortality in chronic kidney disease of uncertain etiology: a cohort study in Medawachchiya, Sri Lanka

Outcome

Type of analysis

Variable

Hazard ratio

95% Confidence interval

p value

Disease progression (CKD stage 1–4)

Sex-stratified, age-adjusted univariate analysis

Alcohol

3.39

1.43–8.04

0.006

Betel

3.61

1.21–10.77

0.021

Hypertension

2.02

0.09–45.34

0.907

NSAID

2.33

0.95–5.71

0.065

Sex-stratified, age-adjusted multivariate (alcohol, betel, hypertension, NSAID) analysis

Alcohol

3.64

0.87–15.23

0.076

Betel

1.94

0.52–7.24

0.325

Hypertension

3.38

1.31–8.72

0.011

NSAID

1.28

0.42–3.90

0.662

Death (CKD stage 1–5)

Sex-stratified, age-adjusted univariate analysis

Hypertension

2.29

0.85–6.17

0.100

CKD stage

3.00

1.71–5.26

0.000

Shrunken kidney

2.74

0.83–9.05

0.097

Sex-stratified, age-adjusted multivariate (hypertension, CKD stage, shrunken kidney) analysis

Hypertension

1.79

0.62–5.17

0.277

CKD stage

2.94

1.57–5.51

0.001

Shrunken kidney

0.80

0.21–3.05

0.742

  1. NSAID nonsteroidal anti-inflammatory drug, CKDu chronic kidney disease of uncertain etiology, Betel betel chewing, Alcohol alcohol consumption