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Table 2 Gross and histopathological examination in the kidney

From: Effect of habitual exercise on renal carcinogenesis by ferric nitrilotriacetate

 

Group II (n = 8)

Group IV (n = 8)

Group VI (n = 7)

Number of gross nodules (diagnosed as RCC)

3

1

2

Number of rats with gross nodule (%)

2 (25.0%)

1 (12.5%)

2 (28.6%)

Number of gross nodules/rat

0.38 ± 0.74

0.13 ± 0.35

0.29 ± 0.00

Mean size of gross nodule (mm2)

3.7 ± 2.2

54.0

13.3 ± 16.6

Number of rats with Mc (%)

2 (25.0%)

7 (87.5%)a

2 (28.6%)b

Number of Mc

2

12

2

Number of Mc/rat

0.25 ± 0.46

1.05 ± 0.93aa

0.29 ± 0.49bb

Mean size of Mc (mm2)

0.14 ± 0.05

0.11 ± 0.17

0.20 ± 0.03

Number of rats with KC (%)

8 (100%)

8 (100%)

7 (100%)

Number of KC/rat

11.5 ± 5.4

28.1 ± 12.9aa

15.7 ± 8.2bb

Number of rats with DT (%)

6 (75.0%)

8 (100%)

6 (85.7%)

Number of DT/rat

1.13 ± 0.99

3.50 ± 2.62aa

2.14 ± 1.21

Number of PTs with BDs

61.3 ± 13.9

52.1 ± 5.9

34.3 ± 17.3aa,bb

Number of BDs

86.0 ± 22.7

82.0 ± 9.4

43.4 ± 12.1aa,bb

  1. RCC renal cell carcinoma, Mc microcarcinoma, KC karyomegalic cell, DT degenerative tubule, PT proximal tubule, BD brown droplet
  2. ap < 0.05, aap < 0.01: significantly different from group II
  3. bp < 0.05, bbp < 0.01: significantly different from group IV