Fig. 2
From: Effect of habitual exercise on renal carcinogenesis by ferric nitrilotriacetate
a White nodule (down arrow) induced in kidney by Fe-NTA in a group II rat. b Renal cell carcinoma induced in kidney by Fe-NTA in a group VI rat. c Renal cell microcarcinoma (down arrow) induced in kidney by Fe-NTA in a group VI rat. d Karyomegalic cell (down arrow) induced in proximal tubule by Fe-NTA in a group II rat. e Degenerative tubule with eosinophilic cytoplasm (down arrows), atypia (filled inverted triangle), and karyomegalic cell (open inverted triangle) induced in kidney by Fe-NTA in a group II rat. f Brown droplets (down arrows) in proximal tubule in a group II rat. g PCNA-positive nuclei in a renal cell carcinoma in a group II rat. h PCNA-positive nuclei (down arrows) in some proximal tubule epithelial cells in a group VI rat. i TUNEL-positive nuclei (down arrow) in some proximal tubule epithelial cells in a group VI rat. Bar 100 μm (c), 50 μm (e, g–i), 20 μm (b, d, f). H&E stain: b–f; Immunohistochemistry for PCNA (g, h) and apoptotic cells by TUNEL (i)