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Fig. 5 | Environmental Health and Preventive Medicine

Fig. 5

From: Long-term administration of the fungus toxin, sterigmatocystin, induces intestinal metaplasia and increases the proliferative activity of PCNA, p53, and MDM2 in the gastric mucosa of aged Mongolian gerbils

Fig. 5

p53 and MDM2 immunostaining images in the gastric mucosa of Mongolian gerbils. a, b Non-treated control gerbils, whose nuclei are negative on p53 and MDM2 immunostaining. c, d p53 and MDM2 expressions are observed in the gastric mucosa from ST-administered gerbils. Faintly stained cells are seen in the mucous glands. The arrows indicate positive nuclei. Stains: p53 immunohistochemistry (a, c), MDM2 immunohistochemistry (b, d). Groups: non-treated control group (a, b), ST 1,000 ppb administration group (c, d)

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Environmental Health and Preventive Medicine

ISSN: 1347-4715

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