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Fig. 4 | Environmental Health and Preventive Medicine

Fig. 4

From: Long-term administration of the fungus toxin, sterigmatocystin, induces intestinal metaplasia and increases the proliferative activity of PCNA, p53, and MDM2 in the gastric mucosa of aged Mongolian gerbils

Fig. 4

Proliferating cell nuclear antigen (PCNA)-immunostaining images of the gastric mucosa of Mongolian gerbils. a Non-treated control animals, whose nuclei show almost negative reaction for PCNA antibody. b, c The gastric mucosa of ST-administered Mongolian gerbils clearly has PCNA-positive nuclei. Stain: PCNA immunohistochemistry (a–c). Groups: non-treated control group (a), ST 1,000 ppb administration group (b), and ST 100 ppb administration group (c)

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