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Fig. 3 | Environmental Health and Preventive Medicine

Fig. 3

From: Long-term administration of the fungus toxin, sterigmatocystin, induces intestinal metaplasia and increases the proliferative activity of PCNA, p53, and MDM2 in the gastric mucosa of aged Mongolian gerbils

Fig. 3

Histopathological findings in the gastric mucosa of Mongolian gerbils. a, b Intestinal metaplasia forming villus-like structures (arrows) in the mucosa of the pyloric antrum. c Erosion events in the antrum mucosa. Not only the gastric epithelium but also the gastric glands were severely damaged. d Polyps consisting of several glands in the mucosa. A large polyp like a cauliflower is found (arrows). Stains: H&E staining (a, c), pH 2.5 Alcian blue staining (b), PAS staining (d). Groups: ST 100 ppb administration group (b), ST 1,000 ppb administration group (a, c, d)

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Environmental Health and Preventive Medicine

ISSN: 1347-4715

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