From: Effect of fluoride exposure on bone metabolism indicators ALP, BALP, and BGP
Group | Fluoride concentration (mg/L) | Number of animals | Content of serum BGP (ng/mL)) | |||
---|---|---|---|---|---|---|
Day 0 | Day 15 | Day 30 | Day 90 | |||
High-dose | 400 | 4 | 1.37 ± 0.66 | 1.31 ± 0.30 | 0.79 ± 0.27* | 0.63 ± 0.11* |
Middle-dose | 150 | 4 | 1.37 ± 0.66 | 1.08 ± 0.61 | 1.10 ± 0.10 | 1.32 ± 0.29* † |
Low-dose | 10 | 4 | 1.37 ± 0.66 | 1.41 ± 0.64 | 0.91 ± 0.10 | 0.72 ± 0.27 |
Control | 0.18 | 4 | 1.37 ± 0.66 | 1.85 ± 0.31 | 1.20 ± 0.16 | 0.86 ± 0.10 |