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Table 4 Serum bone alkaline phosphatase activity in rats in the different sodium fluoride-exposure and control groups over time

From: Effect of fluoride exposure on bone metabolism indicators ALP, BALP, and BGP

Group

Fluoride concentration (mg/L)

Number of animals

Serum BALP activity (King units/100 mL)

Day 0

Day 15

Day 30

Day 90

High-dose

400

4

21.93 ± 3.31

21.21 ± 2.94

25.57 ± 3.58

25.43 ± 2.57

Middle-dose

150

4

21.93 ± 3.31

21.34 ± 2.92

35.29 ± 1.58*

25.13 ± 3.63

Low-dose

10

4

21.93 ± 3.31

27.99 ± 4.67

30.76 ± 3.60

29.81 ± 3.19

Control

0.18

4

21.93 ± 3.31

24.28 ± 2.67

30.29 ± 2.29

28.17 ± 3.28

  1. p < 0.05 compared with the control
  2. Values are given as the mean ± SD
  3. BALP bone alkaline phosphatase