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Table 3 Serum alkaline phosphatase activity in rats in the different sodium fluoride-exposure and control groups over time

From: Effect of fluoride exposure on bone metabolism indicators ALP, BALP, and BGP

Group

Fluoride concentration (mg/L)

Number of animals

Serum ALP activity (King units/100 mL)

Day 0

Day 15

Day 30

Day 90

High-dose

400

4

39.51 ± 2.81

33.05 ± 5.21*

45.78 ± 2.40*

32.26 ± 2.77

Middle-dose

150

4

39.51 ± 2.81

37.92 ± 4.90

55.50 ± 2.15*

30.81 ± 2.82 †

Low-dose

10

4

39.51 ± 2.81

45.13 ± 1.67*

50.71 ± 2.13

35.75 ± 3.84

Control

0.18

4

39.51 ± 2.81

40.18 ± 1.86

50.50 ± 1.59

34.68 ± 2.53

  1. p < 0.05 compared with the control
  2. † p < 0.05 compared with the low-dose group
  3. Values are given as the mean ± SD
  4. ALP alkaline phosphatase