From: Effect of fluoride exposure on bone metabolism indicators ALP, BALP, and BGP
Group | Fluoride concentration (mg/L) | Number of animals | Content of serum fluoride (mg/L) | |||
---|---|---|---|---|---|---|
Day 0 | Day 15 | Day 30 | Day 90 | |||
High-dose | 400 | 4 | 0.11 ± 0.04 | 0.50 ± 0.08* † | 0.95 ± 0.50† | 0.53 ± 0.11* † |
Middle-dose | 150 | 4 | 0.11 ± 0.04 | 0.43 ± 0.10* † | 0.32 ± 0.11* † | 0.28 ± 0.10* † |
Low-dose | 10 | 4 | 0.11 ± 0.04 | 0.23 ± 0.02* | 0.15 ± 0.04* | 0.13 ± 0.03 |
Control | 0.18 | 4 | 0.11 ± 0.04 | 0.12 ± 0.02 | 0.06 ± 0.04 | 0.10 ± 0.05 |