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Table 2 Content of serum fluoride in serum of rats of the different sodium fluoride-exposure and control groups over time

From: Effect of fluoride exposure on bone metabolism indicators ALP, BALP, and BGP

Group

Fluoride concentration (mg/L)

Number of animals

Content of serum fluoride (mg/L)

Day 0

Day 15

Day 30

Day 90

High-dose

400

4

0.11 ± 0.04

0.50 ± 0.08* †

0.95 ± 0.50†

0.53 ± 0.11* †

Middle-dose

150

4

0.11 ± 0.04

0.43 ± 0.10* †

0.32 ± 0.11* †

0.28 ± 0.10* †

Low-dose

10

4

0.11 ± 0.04

0.23 ± 0.02*

0.15 ± 0.04*

0.13 ± 0.03

Control

0.18

4

0.11 ± 0.04

0.12 ± 0.02

0.06 ± 0.04

0.10 ± 0.05

  1. p < 0.05 compared with the control
  2. † p < 0.05 compared with the low-dose group
  3. Values are given as the mean ± SD