Skip to main content

Table 2 Age-adjusted analysis for factors associated with cancer mortality: all cancers, nonliver cancers, and liver cancers

From: History of blood transfusion before 1990 is associated with increased risk for cancer mortality independently of liver disease: a prospective long-term follow-up study

 

Men

Women

All

n

HR (95% CI)

P value

n

HR (95% CI)

P value

HR (95% CI)

P value

Cancer (all)

 Smoking status

  Never

61

1.00

 

147

1.00

 

1.00

 

  Smoker

194

2.01 (1.51–2.69)

<0.0001

8

1.75 (0.86–3.57)

0.12

1.97 (1.51–2.57)

<0.0001

  Ex-smoker

71

1.43 (1.09–1.89)

0.0107

2

1.61 (0.33–7.74)

0.55

1.44 (1.10–1.89)

0.0089

 Alcohol intake

  Never

59

1.00

 

124

1.00

 

1.00

 

  Drinker

243

0.77 (0.52–1.13)

0.18

49

0.60 (0.28–1.26)

0.18

0.74 (0.53–1.05)

0.0888

  Ex-drinker

29

1.16 (0.75–1.82)

0.51

8

2.23 (1.09–4.56)

0.0279

1.36 (0.92–2.02)

0.12

 History of external injury

  No

256

1.00

 

140

1.00

 

1.00

 

  Yes

72

0.87 (0.67–1.13)

0.3

49

1.42 (1.02–1.96)

0.0369

1.04 (0.85–1.27)

0.72

 History of abdominal surgery

  No

250

1.00

 

113

1.00

 

1.00

 

  Yes

90

1.08 (0.85–1.37)

0.55

82

1.09 (0.82–1.45)

0.55

1.08 (0.90–1.30)

0.41

 History of liver disease

  No

308

1.00

 

177

1.00

 

1.00

 

  Yes

17

1.28 (0.79–2.09)

0.32

8

1.47 (0.72–2.99)

0.29

1.34 (0.89–2.00)

0.16

 History of blood transfusion

  No

296

1.00

 

153

1.00

 

1.00

 

  Yes

37

1.33 (0.94–1.87)

0.11

34

1.91 (1.32–2.77)

0.0007

1.55 (1.20–1.99)

0.0006

 History of pregnancy

  No

   

5

1.00

   

  Yes

   

169

0.42 (0.17–1.02)

0.0562

  

Cancer (nonliver)

 Smoking status

  Never

58

1.00

 

137

1.00

 

1.00

 

  Smoker

185

2.02 (1.50–2.71)

<0.0001

8

1.88 (0.92–3.84)

0.0827

2.00 (1.52–2.62)

<0.0001

  Ex-smoker

68

1.44 (1.08–1.91)

0.0116

2

1.61 (0.33–7.74)

0.55

1.44 (1.09–1.90)

0.0096

 Alcohol intake

  Never

58

1.00

 

116

1.00

 

1.00

 

  Drinker

233

0.86 (0.56–1.30)

0.46

48

0.67 (0.30–1.48)

0.32

0.83 (0.57–1.20)

0.31

  Ex-drinker

25

1.02 (0.64–1.63)

0.95

7

2.09 (0.98–4.49)

0.0575

1.21 (0.80–1.82)

0.37

 History of external injury

  No

249

1.00

 

133

1.00

 

1.00

 

  Yes

64

0.80 (0.60–1.05)

0.1

45

1.37 (0.97–1.92)

0.0711

0.97 (0.78–1.20)

0.77

 History of abdominal surgery

  No

239

1.00

 

108

1.00

 

1.00

 

  Yes

86

1.08 (0.84–1.38)

0.56

74

1.03 (0.77–1.39)

0.85

1.06 (0.87–1.28)

0.57

 History of liver disease

  No

297

1.00

 

168

1.00

 

1.00

 

  Yes

13

1.02 (0.58–1.77)

0.96

6

1.16 (0.52–2.63)

0.72

1.06 (0.67–1.68)

0.81

 History of blood transfusion

  No

286

1.00

 

144

1.00

 

1.00

 

  Yes

32

1.19 (0.82–1.71)

0.36

32

1.91 (1.30–2.80)

0.0009

1.46 (1.12–1.90)

0.005

 History of pregnancy

  No

   

4

1.00

   

  Yes

   

159

0.49 (0.18–1.33)

0.1615

  

Cancer (liver)

 History of liver disease

  No

11

1.00

 

9

1.00

 

1.00

 

  Yes

4

8.27 (2.63–26.05)

0.0003

2

7.21 (1.55–33.51)

0.0117

7.93 (3.18–19.81)

<0.0001

 History of blood transfusion

  No

10

1.00

 

9

1.00

 

1.00

 

  Yes

5

5.41 (1.84–15.88)

0.0021

2

1.88 (0.41–8.70)

0.42

3.56 (1.49–8.50)

0.0042

  1. People with history of cancer before participation in the cohort were excluded from this analysis
  2. HR hazard ratio, CI confidence interval