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Table 1 Cancer caused by infectious agents (adapted and modified from the IARC [4])

From: Formation of 8-nitroguanine, a nitrative DNA lesion, in inflammation-related carcinogenesis and its significance

Infectious agents

IARC classificationa

Cancer site

Number of cancer cases

Percentage of cancer cases worldwide

Bacterium

 Helicobacter pylori

1

Stomach

490,000

5.4

Viruses

 HPVb

  High-risk types

1

Cervix and other sites

550,000

6.1

  Low-risk types

2B

 HBV and HCV

1

Liver

390,000

4.3

 EBV

1

Lymphoma

99,000

1.1

Nasopharyngeal carcinoma

 HHV-8

2A

Kaposi sarcoma

54,000

0.6

 HTLV-1

1

Leukemia

9,000

0.1

Parasites

 Schistosoma haematobium

1

Bladder

2,700

0.1

 Liver flukes

  Opisthorchis viverrini

1

Intra- and extrahepatic bile ducts

800

 

  Clonorchis sinensis

2A

Total infection-related cancers

  

1,600,000

17.7

Total cancers (1995)

  

9,000,000

100

  1. IARC International Agency for Research on Cancer
  2. aIARC classification: Group 1, carcinogenic to humans; Group 2A, probably carcinogenic to humans; Group 2B, possibly carcinogenic to humans
  3. bHPV Human papillomavirus, HBV hepatitis B virus, HCV hepatitis C virus, HHV-8 human herpesvirus-8, HTLV-1 human T-lymphotropic virus type 1