Baseline characteristics of female study participants | Non-MS, n = 894 [mean (SD)] | MS, n = 63 [mean (SD)] | p |
---|---|---|---|
Age (years) | 50.6 (9.5) | 56.7 (9.6) | <0.0001 |
Body mass index (kg/m2) | 21.4 (2.8) | 25.8 (3.3) | <0.0001 |
Body fat (%) | 26.1 (5.4) | 33.9 (5.8) | <0.0001 |
Waist circumference (cm) | 77.9 (8.1) | 90.0 (7.8) | <0.0001 |
Systolic blood pressure (mmHg) | 110.0 (15.2) | 131.3 (20.6) | <0.0001 |
Diastolic blood pressure (mmHg) | 68.8 (9.3) | 81.1 (12.3) | <0.0001 |
Fasting glucose (mg/dL) | 88.0 (8.5) | 104.4 (21.7) | <0.0001 |
Triglycerides (mg/dL) | 70 (54, 95)a | 129 (90, 189)a | <0.0001 |
HDL cholesterol (mg/dL) | 68.1 (14.1) | 51.9 (12.4) | <0.0001 |
High-sensitivity CRP (mg/L) | 0.20 (0.10, 0.38)a | 0.50 (0.25, 0.90)a | 0.0001 |
Gamma glutamyltransferase (U/L) | 17 (13, 23)a | 27 (18, 41)a | <0.0001 |
Alanine aminotransferase (U/L) | 15 (12, 19)a | 22 (16, 31)a | <0.0001 |
White blood cell count (L−6) | 4795 (1263) | 5379 (1113) | <0.001 |
LDL cholesterol (mg/dL) | 119.6 (28.3) | 140.9 (29.2) | <0.0001 |
Uric acid (mg/dL) | 4.4 (0.9) | 5.3 (1.2) | <0.0001 |
Hemoglobin A1c (%) | 5.0 (0.3) | 5.5 (0.8) | <0.0001 |
Vital capacity (%) | 96.1 (11.4) | 95.6 (15.0) | ns |
FEV1/FVC (%) | 82.5 (5.6) | 81.2 (5.4) | ns |
Heart rate (/min) | 60.0 (7.9) | 63.1 (9.6) | 0.004 |
eGFR (mL/min/1.73 m2) | 80.4 (13.1) | 75.4 (13.0) | 0.003 |
n (%) | n (%) | p | |
---|---|---|---|
Antihypertensive medication | 54 (6.0) | 31 (49.2) | <0.0001 |
Antidiabetic medication | 4 (0.4) | 7 (11.1) | <0.0001 |
Current smoker | 56 (6.3) | 4 (6.3) | ns |
Everyday drinker | 129 (14.4) | 9 (14.3) | ns |
JMS | 0 (0) | 20 (31.7) | <0.0001 |
Diabetes | 6 (0.7) | 9 (14.3) | <0.0001 |
Cardiovascular disease | 25 (2.8) | 4 (6.3) | ns |