Baseline characteristics of male study participants | Non-MS, n = 1413 [mean (SD)] | MS, n = 238 [mean (SD)] | p |
---|---|---|---|
Age (years) | 51.2 (9.3) | 53.1 (8.4) | 0.003 |
Body mass index (kg/m2) | 22.7 (2.6) | 26.7 (3.1) | <0.0001 |
Body fat (%) | 21.1 (4.5) | 27.2 (4.6) | <0.0001 |
Waist circumference (cm) | 82.5 (7.1) | 94.1 (6.8) | <0.0001 |
Systolic blood pressure (mmHg) | 120.1 (16.5) | 134.1 (15.6) | <0.0001 |
Diastolic blood pressure (mmHg) | 76.5 (10.2) | 84.2 (10.2) | <0.0001 |
Fasting glucose (mg/dL) | 93.7 (12.0) | 107.4 (18.5) | <0.0001 |
Triglycerides (mg/dL) | 95 (70, 128)a | 171 (138, 228)a | <0.0001 |
HDL cholesterol (mg/dL) | 59.3 (14.1) | 47.1 (10.4) | <0.0001 |
High-sensitivity CRP (mg/L) | 0.27 (0.15, 0.53)a | 0.62 (0.38, 1.27)a | <0.0001 |
Gamma glutamyltransferase (U/L) | 33 (23, 52)a | 51 (35, 79)a | <0.0001 |
Alanine aminotransferase (U/L) | 21 (16, 28)a | 30 (23, 44)a | <0.0001 |
White blood cell count (L−6) | 5438 (1435) | 6242 (1494) | <0.0001 |
LDL cholesterol (mg/dL) | 119.0 (28.7) | 127.1 (30.7) | <0.0001 |
Uric acid (mg/dL) | 6.1 (1.3) | 6.6 (1.4) | <0.0001 |
Hemoglobin A1c (%) | 5.0 (0.5) | 5.5 (0.7) | <0.0001 |
Vital capacity (%) | 96.3 (11.0) | 92.4 (11.3) | <0.0001 |
FEV1/FVC (%) | 80.5 (6.0) | 80.3 (6.0) | ns |
Heart rate (/min) | 58.3 (8.8) | 63.2 (9.5) | <0.0001 |
eGFR (mL/min per 1.73 m2) | 78.6 (12.7) | 76.0 (14.0) | 0.004 |
n (%) | n (%) | p | |
---|---|---|---|
Antihypertensive medication | 222 (15.7) | 88 (37.0) | <0.0001 |
Antidiabetic medication | 35 (2.5) | 29 (12.2) | <0.0001 |
Current smoker | 467 (33.0) | 94 (39.5) | <0.05 |
Everyday drinker | 748 (52.8) | 120 (50.4) | ns |
JMS | 51 (3.6) | 163 (68.5) | <0.0001 |
Diabetes | 54 (3.8) | 40 (16.8) | <0.0001 |
Cardiovascular disease | 78 (5.5) | 24 (10.1) | <0.01 |