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Table 2 Fiber numbers in lungs and their proportions

From: Behavior of rock wool in lungs after exposure by nasal inhalation in rats

Sacrificed rat group

Total fibers

Fibers shorter than or equal to 5 μm (L ≤ 5 μm)

Fibers longer than 5 μm and shorter than or equal to 20 μm (5 μm < L ≤ 20 μm)

Fibers longer than 20 μm (L > 20 μm)

WHO fibers

Geometric mean (GSD)

%

Geometric mean (GSD)

%

Geometric mean (GSD)

%

Geometric mean (GSD)

%

Geometric mean (GSD)

%

Shortly-after group

9.43 (1.13)

100.0

2.12 (1.24)

100.0

6.08 (1.13)

100.0

1.21 (1.14)

100.0

7.09 (1.12)

100.0

1-Week-after group

7.42 (1.35)

78.7

2.04 (1.50)

96.3

4.75 (1.34)

78.2

0.54 (1.83)

44.9

5.20 (1.36)

73.3

2-Weeks-after group

7.68 (1.17)

81.5

2.12 (1.16)

100.3

5.07 (1.21)

83.4

0.42 (1.73)

34.7

5.45 (1.20)

76.9

4-Weeks-after group

5.05 (1.23)a,c

53.6

1.59 (1.48)

74.9

3.13 (1.24)a,c

51.5

0.22 (2.27)a

17.9

3.38 (1.25)a,b,c

47.7

  1. Geometric mean: ×105/lung, WHO fiber: length > 5 μm and width < 3 μm
  2. %: percentage assuming the value of the shortly-after group to be 100%
  3. n = 5, L length of fiber (μm)
  4. GSD geometric standard deviation
  5. aComparison with shortly-after group (P < 0.05)
  6. bComparison with 1-week-after group (P < 0.05)
  7. cComparison with 2-weeks-after group (P < 0.05)