Exposure assessment of phthalate esters in Japanese pregnant women by using urinary metabolite analysis

Table 1 Inter- and intraindividual variance and intraclass correlation coefficient (ICC) of each urinary phthalate metabolite concentrations

Urinary metabolites	Interindividual	Intraindividual	ICC^a
MMP	0.07215	0.05477	0.569
MEP	0.06827	0.07789	0.467
MnBP	0.06876	0.03022	0.695
MBzP	0.06605	0.1739	0.275
MEHP	0.0462	0.04371	0.514
MEHHP	0.04404	0.05944	0.426
MEOHP	0.04009	0.05736	0.411

n = 48, four spot urine samples from 12 pregnant women, within 1–6 weeks intervals during 5–12 sampling period
Log-transformed urinary metabolite concentrations were used in this statistical analysis because the seven phthalate monoester concentrations in 48 single spot urine samples from 12 pregnant women were log-normally distributed
^aICC = Interindividual variance/(interindividual variance + intraindividual variance)

ISSN: 1347-4715