Fig. 2
From: Epigenetic abnormalities in cardiac hypertrophy and heart failure
Epigenetic changes and transcriptional activity. Suppression of gene expression (OFF) is correlated with the methylation (Met) of genomic DNA, deacetylation of histones, and methylation of H3-K9. In contrast, activation of gene expression (ON) is associated with unmethylated genomic DNA, acetylated (Ac) histones, and methylated H3-K4