Basic characteristics of study cohortb | Quartile of Spm concentration (range) | P for effectc | |||
---|---|---|---|---|---|
Q1 (≤0.033) (n = 155) | Q2 (≤0.046) (n = 156) | Q3 (≤0.063) (n = 156) | Q4 (>0.063) (n = 155) | ||
Age (years) | 49.3 ± 6.3 | 50.8 ± 6.7 | 51.4 ± 6.1 | 51.0 ± 6.0 | 0.015 |
Body mass index (kg/m2) | 23.1 ± 2.6 | 23.2 ± 2.6 | 23.7 ± 2.6 | 23.5 ± 2.5 | 0.201 |
Fasting plasma glucose (mmol/l) | 5.58 ± 1.23 | 5.76 ± 1.20 | 5.85 ± 1.33 | 5.85 ± 1.21 | 0.195 |
Fasting plasma insulin (μU/ml) | 5.57 ± 3.03 | 5.51 ± 2.94 | 6.54 ± 6.40 | 6.14 ± 5.80 | 0.186 |
HOMA–IRd | 1.39 ± 0.80 | 1.43 ± 0.86 | 1.67 ± 1.45 | 1.60 ± 1.55 | 0.119 |
Fructosamine (μmol/l) | 257 ± 37 | 253 ± 31 | 257 ± 39 | 256 ± 40 | 0.732 |
Polyamine-to-hemoglobin ratio (μmol/g) | |||||
Spd + Spm | 0.76 ± 0.32 | 0.94 ± 0.24 | 1.16 ± 0.81 | 1.35 ± 0.63 | <0.001 |
Spm | 0.23 ± 0.11 | 0.39 ± 0.04 | 0.54 ± 0.05 | 0.91 ± 0.56 | <0.001 |
Smoking status (% of subjects) | |||||
Never | 32.3 | 39.7 | 35.3 | 32.3 | 0.831 |
Past | 22.6 | 20.5 | 23.1 | 24.5 | |
Current | 45.2 | 39.7 | 41.7 | 43.2 | |
Drinking status (% of subjects) | |||||
None | 25.8 | 26.3 | 35.9 | 30.3 | 0.061 |
Light | 28.4 | 26.9 | 14.1 | 23.2 | |
Moderate | 22.6 | 16.7 | 25.0 | 19.4 | |
Moderate | 23.2 | 30.1 | 25.0 | 27.1 | |
Leisure-time physical activity (% of subjects) | |||||
Not very active | 81.6 | 77.3 | 75.0 | 77.0 | 0.726 |
Somewhat active | 10.4 | 14.3 | 16.7 | 16.4 | |
Regularly active | 7.8 | 8.4 | 8.3 | 6.6 | |
Present history of chronic disease (% of subjects)e | |||||
Yes | 14.8 | 19.9 | 15.4 | 20.0 | 0.472 |