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Table 1 Basic characteristics of 622 men according to quartiled Spm + Spd concentrationsa

From: Association of glycemic profiles with whole blood polyamine among middle-aged Japanese men: colorimetric assay using oat and barley seedling polyamine oxidase

Basic characteristics of study cohortb

Quartile of Spd + Spm concentration (range)b

P for effectc

Q1 (≤0.082) (n = 155)

Q2 (≤0.102) (n = 156)

Q3 (≤0.121) (n = 156)

Q4 (>0.121) (n = 155)

Age (years)

49.5 ± 6.6

50.0 ± 6.3

51.7 ± 6.0

51.3 ± 6.1

0.004

Body mass index (kg/m2)

23.0 ± 2.4

23.3 ± 2.6

23.5 ± 2.6

23.7 ± 2.6

0.119

Fasting plasma glucose (mmol/l)

5.62 ± 1.13

5.54 ± 0.75

5.93 ± 1.21

5.97 ± 1.67

0.003

Fasting plasma insulin (μU/ml)

5.35 ± 2.86

5.89 ± 6.15

6.06 ± 3.28

6.45 ± 5.99

0.240

HOMA–IRd

1.34 ± 0.74

1.45 ± 1.36

1.62 ± 0.99

1.69 ± 1.58

0.042

Fructosamine (μmol/l)

251 ± 34

255 ± 26

257 ± 38

260 ± 47

0.145

Polyamine-to-hemoglobin ratio (μmol/g)

 Spd + Spm

0.060 ± 0.023

0.092 ± 0.005

0.110 ± 0.006

0.158 ± 0.093

<0.001

 Spm

0.034 ± 0.022

0.042 ± 0.018

0.053 ± 0.019

0.078 ± 0.060

<0.001

Smoking status (% of subjects)

 Never

35.5

35.9

35.9

32.3

0.882

 Past

19.4

21.8

24.4

25.2

 

 Current

45.2

42.3

39.7

42.6

 

Drinking status (% of subjects)

 None

27.1

27.6

29.5

34.2

0.094

 Light

20.6

27.6

23.1

21.3

 

 Moderate

20.6

26.9

16.7

19.4

 

 Heavy

31.6

17.9

30.8

25.2

 

Leisure-time physical activity (% of subjects)

 Not very active

79.2

76.5

76.8

78.6

0.575

 Somewhat active

13.0

12.4

16.8

15.6

 

 Regularly active

7.8

11.1

6.5

5.8

 

Present history of chronic disease (% of subjects)e

 Yes

14.8

16.0

21.2

18.1

0.481

  1. Spd, Spermidine; Spm, spermine
  2. aQuartiled Spm + Spd concentrations are represented by polyamine-to-hemoglobin ratio
  3. bValues in the upper part of the table only are given as means ± standard deviation
  4. cP value by one-factor analysis of variance for continuous variables, and chi-square test for categorical variables
  5. dHomeostasis model assessment–insulin resistance
  6. eAny disease under treatment, including hypertension, diabetes, dyslipidemia, stroke, heart disease, or hyperuricemia